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Chromosome 15 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 15 spans about 101 million base pairs (the building material of DNA) and represents between 3% and 3.5% of the total DNA in cells. Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 15 likely contains between 700 and 900 genes. ==Genes== The human leukocyte antigen gene for β2-microglobulin is found at chromosome 15. The following are some of the genes located on chromosome 15: * CAPN3: Calpain 3 (limb-girdle muscular dystrophy type 2A) * CHP: Calcium binding protein P22 * FAH: fumarylacetoacetate hydrolase (fumarylacetoacetase) * FBN1: fibrillin 1 (Marfan syndrome) * HEXA: hexosaminidase A (alpha polypeptide)(Tay-Sachs disease) * IVD: isovaleryl Coenzyme A dehydrogenase * MCPH4: microcephaly, primary autosomal recessive 4 * OCA2: oculocutaneous albinism II (pink-eye dilution homolog, mouse) * RAD51: RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) * STRC: stereocilin * UBE3A: ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome) * PML: promyelocytic leukemia protein (involved in t(15,17) with RARalpha, predominant cause of acute promyelocytic leukemia. * SLC24A5: the gene responsible for at least 1/3 of the skin color differences between races, expressed in the brain and the nervous system * EYCL3 Eye color 3, BROWN - location: 15q11-q15 (note eye colour is a polygenic trait) () * EYCL2 Eye color 2, Determines the positioning of melanocytes on the iris (note eye colour is a polygenic trait) 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Chromosome 15 (human)」の詳細全文を読む スポンサード リンク
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